BDBM50450872 CHEMBL4213400

SMILES CC(C)C(CO)Nc1nc(Nc2ccc(cc2)N2CCNCC2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=PCKCQHTXFTYJSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450872   

TargetEpidermal growth factor receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50450872(CHEMBL4213400)
Affinity DataIC50: 78nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed