BDBM50451031 CHEMBL4217207

SMILES CNC(=O)c1cc(Oc2ccc(cc2)C2=NNC(C2)c2cccc(Br)c2)ccn1

InChI Key InChIKey=SVZJDNDOMDBENZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50451031   

TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50451031(CHEMBL4217207)
Affinity DataIC50: 560nMAssay Description:Inhibition of VEGFR2 (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50451031(CHEMBL4217207)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of BRAF (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50451031(CHEMBL4217207)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of CRAF (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50451031(CHEMBL4217207)
Affinity DataIC50: 540nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50451031(CHEMBL4217207)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50451031(CHEMBL4217207)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of FLT3 (unknown origin) incubated for 10 mins using FAM-labeled peptide and ATP by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed