BDBM50451372 CHEMBL4217405

SMILES C[C@H]([C@@H](NC(=O)N1CCN(C(=O)C1)c1ccc(F)cc1C)C(=O)Nc1cc(CN(C)C)ccc1OC(F)(F)F)c1c[nH]c2ccccc12

InChI Key InChIKey=HUSUOHXIMXAZBI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50451372   

TargetSomatostatin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50451372(CHEMBL4217405)
Affinity DataIC50: 5.10E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR1 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50451372(CHEMBL4217405)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR4 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50451372(CHEMBL4217405)
Affinity DataIC50: 360nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR3 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50451372(CHEMBL4217405)
Affinity DataIC50: 0.170nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR2 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50451372(CHEMBL4217405)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [125I]somatostatin-14 (Tyr11) from human SSTR5 expressed in CHO dhfr cell membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed