BDBM50451467 CHEMBL4203767

SMILES Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)N[C@@H](CO)C(O)=O

InChI Key InChIKey=REFXTMLPVWSINW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451467   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451467(CHEMBL4203767)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human C-terminal FLT3 ITD mutant (571 to 993 residues) after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451467(CHEMBL4203767)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human HCK SH3-SH2-KD (75 to 526 residues) after 20 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed