BDBM50451468 CHEMBL4207885

SMILES [H][C@@]1(CCOC1=O)N[C@H]1CC[C@H](CC1)n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12

InChI Key InChIKey=GDQTYFYNHJDRBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451468   

TargetTyrosine-protein kinase HCK(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451468(CHEMBL4207885)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human HCK SH3-SH2-KD (75 to 526 residues) after 20 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451468(CHEMBL4207885)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human C-terminal FLT3 ITD mutant (571 to 993 residues) after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed