BDBM50451476 CHEMBL4202763

SMILES Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CC[C@@H](CC1)NCC(O)=O

InChI Key InChIKey=UPOHPTDDNIQADZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451476   

TargetTyrosine-protein kinase HCK(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451476(CHEMBL4202763)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human HCK SH3-SH2-KD (75 to 526 residues) after 20 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Riken Center For Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM50451476(CHEMBL4202763)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human C-terminal FLT3 ITD mutant (571 to 993 residues) after 90 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed