BDBM50451643 CHEMBL4204051

SMILES Fc1ccccc1-n1nc(C(=O)NCc2ccccc2OCC(F)(F)F)c(Br)c1C1CC1

InChI Key InChIKey=SQUNSKHKMIEJHJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451643   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451643(CHEMBL4204051)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human Cav3.1 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451643(CHEMBL4204051)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human Cav3.3 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451643(CHEMBL4204051)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant human Cav3.2 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed