BDBM50451646 CHEMBL4208390

SMILES Brc1c(nn(c1-c1ccccc1)-c1ccccc1)C(=O)NCc1ccccc1-n1cccn1

InChI Key InChIKey=PYIIKMACNHNPIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451646   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451646(CHEMBL4208390)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human Cav3.1 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451646(CHEMBL4208390)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human Cav3.2 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451646(CHEMBL4208390)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human Cav3.3 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed