BDBM50451650 CHEMBL4216669

SMILES FC(F)(F)COc1ccccc1CNC(=O)c1nn(c(c1C=C)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=SJYPETBHKFXKTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451650   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451650(CHEMBL4216669)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human Cav3.1 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451650(CHEMBL4216669)
Affinity DataIC50: 850nMAssay Description:Inhibition of recombinant human Cav3.2 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451650(CHEMBL4216669)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human Cav3.3 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed