BDBM50451675 CHEMBL4218705

SMILES CCN1CCN(Cc2ccc(Nc3cc(ncn3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nn2)CC1

InChI Key InChIKey=DRMSOWKGUXWJOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451675   

TargetCyclin-dependent kinase 4(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451675(CHEMBL4218705)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK4 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451675(CHEMBL4218705)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of CDK1 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed