BDBM50451680 CHEMBL4207218

SMILES CCN1CCC(Cc2cnc(Nc3cc(ncn3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)cn2)CC1

InChI Key InChIKey=UQNXGQYESHUBBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451680   

TargetCyclin-dependent kinase 4(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451680(CHEMBL4207218)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of CDK4 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451680(CHEMBL4207218)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of CDK6 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Shanghai Haihe Pharmaceutial

Curated by ChEMBL
LigandPNGBDBM50451680(CHEMBL4207218)
Affinity DataIC50: 134nMAssay Description:Inhibition of CDK1 (unknown origin) using U-light as substrate preincubated for 1 hr followed by EDTA addition measured after 1 hr by LANCE Ultra kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed