BDBM50451865 CHEMBL4216287

SMILES FC1(F)CC(C1)NC(=O)[C@@]1(CCc2ccccc12)N(C(=O)[C@@H]1CCC(=O)N1c1cc(ccn1)C#N)c1ccccc1

InChI Key InChIKey=VFQDOSCWBPFWSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50451865   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe

Curated by ChEMBL
LigandPNGBDBM50451865(CHEMBL4216287)
Affinity DataIC50: 260nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate as substrate after 60 mins by resazurin dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed