BDBM50451905 CHEMBL4217423

SMILES COc1ccc2c(c1)sc1nc(O)c(Cc3ccccc3)c(=O)n21

InChI Key InChIKey=CASSUSGWWVGPQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50451905   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50451905(CHEMBL4217423)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SHP2 F285S mutant (1 to 525 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed