BDBM50451906 CHEMBL4210897

SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(O)cc2)c2ncn(C3CCCCC3)c2n1

InChI Key InChIKey=KOGLUWUFJRYZSL-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451906   

TargetPlatelet-derived growth factor receptor alpha(Human)
Palack£

Curated by ChEMBL

LigandBDBM50451906(CHEMBL4210897)Copy SMILESCopy InChI

Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-His6 tagged PDGFRalpha (Q551 to L1089 residues) expressed in Sf9 insect cells using poly(Ala,Glu,Lys,T...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Palack£

Curated by ChEMBL

LigandBDBM50451906(CHEMBL4210897)Copy SMILESCopy InChI

Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL