BDBM50451913 CHEMBL4214781

SMILES COc1ccc(Cn2cnc3c(Nc4cccc(Cl)c4)nc(N[C@H]4CC[C@H](N)CC4)nc23)cc1

InChI Key InChIKey=UHMSQHCBPDRWJC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451913   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Palack£

Curated by ChEMBL

LigandBDBM50451913(CHEMBL4214781)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in baculovirus infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
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TargetPlatelet-derived growth factor receptor alpha(Human)
Palack£

Curated by ChEMBL

LigandBDBM50451913(CHEMBL4214781)Copy SMILESCopy InChI

Affinity DataIC50: 7.66E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-His6 tagged PDGFRalpha (Q551 to L1089 residues) expressed in Sf9 insect cells using poly(Ala,Glu,Lys,T...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL