BDBM50452025 CHEMBL4213123

SMILES C(Nc1ccc2nsnc2c1)c1cccs1

InChI Key InChIKey=VEKMOMFCKATZHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452025   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50452025(CHEMBL4213123)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50452025(CHEMBL4213123)
Affinity DataIC50: 4.83E+4nMAssay Description:Inhibition of GST-tagged PTP1B (unknown origin) using pNPP as substrate measured for 3 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed