BDBM50452206 CHEMBL4209385::US10647727, Example 4

SMILES Cn1ncc2c(NCc3ccc(cc3)C(F)(F)F)nc(Cl)nc12

InChI Key InChIKey=OCJUFNDXDHXTIL-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452206   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck

Curated by ChEMBL

LigandBDBM50452206(CHEMBL4209385 | US10647727, Example 4)Copy SMILESCopy InChI

Affinity DataKi:  2.34E+3nMAssay Description:Binding affinity to PDE2 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
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TargetPhosphodiesterase(Rhesus macaque)
Merck Sharp & Dohme

US Patent

LigandBDBM50452206(CHEMBL4209385 | US10647727, Example 4)Copy SMILESCopy InChI

Affinity DataKi:  2.34E+3nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/25/2021
Entry Details
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