BDBM50452708 CHEMBL4202546

SMILES Nc1cc(nc(Nc2ccc(CN3CCOCC3)cc2)n1)-c1cccc(c1CO)-n1ccc2cc(cc(F)c2c1=O)C1CC1

InChI Key InChIKey=KCJDKKDHBGQPRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452708   

TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50452708(CHEMBL4202546)
Affinity DataIC50: 309nMAssay Description:Inhibition of His-tagged lambda phosphatase pre-treated N-terminal DYKDDDDK tagged and biotinylated BTK unactivated form (unknown origin) using FITC-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50452708(CHEMBL4202546)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged and biotinylated BTK activated form (unknown origin) using FITC-labeled Srctide substrate and ATP by microfl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed