BDBM50452823 CHEMBL4214333

SMILES Cc1nc2c(OCc3ccccc3C)cccn2c1-c1ccncc1

InChI Key InChIKey=ZEZSYOUSBABXTH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452823   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50452823(CHEMBL4214333)Copy SMILESCopy InChI

Affinity DataIC50: 7.10E+3nMAssay Description:Modulatory activity against gamma-secretase in human SK-N-BE(2) cells assessed as reduction in amyloid beta 42 production after 6 hrs by sandwich ELI...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
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