BDBM50453595 CHEMBL172333

SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)OC\C=C\c2ccccc2)c1

InChI Key InChIKey=UVAWSHXHDMJZMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453595   

TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453595(CHEMBL172333)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453595(CHEMBL172333)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed