BDBM50453995 CHEMBL4212779

SMILES COc1cccc(CNS(=O)(=O)c2cnc3ccc(nn23)-c2cncc(F)c2)c1

InChI Key InChIKey=FDKVWSDRZJCVGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453995   

TargetTumor necrosis factor(Human)
Padmashri Vikhe Patil College of Arts

Curated by ChEMBL
LigandPNGBDBM50453995(CHEMBL4212779)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of LPS-induced TNF-alpha production in human PBMC preincubated for 30 mins followed by LPS addition measured after 5 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed