BDBM50454143 CHEMBL4205710

SMILES COc1ccc(cc1)C(N(C)C(=O)c1ccc(=O)[nH]c1)C(=O)Nc1ccc2c(CCC2(C)C)c1

InChI Key InChIKey=HBPLCOVCXZOVDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454143   

TargetNuclear receptor ROR-gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454143(CHEMBL4205710)
Affinity DataIC50: 84nMAssay Description:Displacement of BODIPY-cholesterol from human His-tagged RORgammat after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454143(CHEMBL4205710)
Affinity DataIC50: 190nMAssay Description:Inverse agonist activity at RORgammat in human Jurkat cells assessed as inhibition of transcriptional activity after overnight incubation by human IL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed