BDBM50454150 CHEMBL4216994

SMILES CCCN(C(C(=O)Nc1ccc(cc1)C(C)(C)C)c1ccc(OC)cc1)C(=O)c1ccc(=O)[nH]c1

InChI Key InChIKey=GBZISXYXYVOTCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454150   

TargetNuclear receptor ROR-gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454150(CHEMBL4216994)
Affinity DataIC50: 230nMAssay Description:Displacement of BODIPY-cholesterol from human His-tagged RORgammat after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454150(CHEMBL4216994)
Affinity DataIC50: 370nMAssay Description:Inverse agonist activity at RORgammat in human Jurkat cells assessed as inhibition of transcriptional activity after overnight incubation by human IL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed