BDBM50454595 CHEMBL4214874

SMILES Cc1nnc(o1)-c1ccc(O[C@H]2CC[C@@H](CC2)NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1

InChI Key InChIKey=AFUUIIKEMWORBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454595   

TargetBifunctional epoxide hydrolase 2(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50454595(CHEMBL4214874)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using CMNPC substrate by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50454595(CHEMBL4214874)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human FAAH expressed in baculovirus-infected High Five cells S9 fraction using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed