BDBM50454598 CHEMBL4215208

SMILES O=C(Nc1ccc(OC(F)(F)F)cc1)N[C@H]1CC[C@H](Oc2ccc(C(=O)OCc3ccccc3)cc2)CC1

InChI Key InChIKey=IEOQZCMTPHDRLT-UHFFFAOYSA-N

Data  1 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50454598   

TargetBifunctional epoxide hydrolase 2(Rat)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of soluble epoxide in rat brain microsomes using CMNPC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of soluble epoxide in mouse brain microsomes using CMNPC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using CMNPC substrate by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 24nMAssay Description:Inhibition of human FAAH expressed in baculovirus-infected High Five cells S9 fraction using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataKi:  43nMAssay Description:Competitive inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using varying CMN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 510nMAssay Description:Inhibition of FAAH in mouse brain microsomes using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpoxide hydrolase 1(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal epoxide hydrolase (unknown origin) expressed in baculovirus system using CMNMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAAH in rat brain microsomes using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetArylacetamide deacetylase(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AADAC (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCocaine esterase(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human carboxylesterase 2 expressed in baculovirus system using CMNA substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerum paraoxonase/arylesterase 1(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PON1 (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human carboxylesterase 1 expressed in baculovirus system using CMNA substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerum paraoxonase/lactonase 3(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PON3 (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerum paraoxonase/arylesterase 2(Human)
University of California Davis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50454598BDBM50454598(CHEMBL4215208)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PON2 (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed