BDBM50454873 CHEMBL4214470

SMILES N[C@H]1CC[C@H](CC1)NCc1ccn2nc(nc(Nc3ccncc3F)c12)-c1ccccn1

InChI Key InChIKey=LZJABIHXXPLMEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454873   

TargetTGF-beta receptor type-1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50454873(CHEMBL4214470)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50454873(CHEMBL4214470)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild type His-tagged TGFbetaR2 (unknown origin) after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed