BDBM50455023 CHEMBL4204145

SMILES Fc1ccc(cc1)S(=O)(=O)N1CCCN(C1=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=GWYLJLKVVXHGKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455023   

TargetNADPH oxidase 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50455023(CHEMBL4204145)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Nox4 in HASMCs assessed as reduction in TGFbeta-induced increase in smooth muscle alpha actin level pretreated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed