BDBM50455491 CHEMBL4208993

SMILES CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)-c1cnc(C)cn1

InChI Key InChIKey=ZMMRLWSKMGPWLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455491   

TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455491(CHEMBL4208993)
Affinity DataIC50: 126nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455491(CHEMBL4208993)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed