BDBM50455616 CHEMBL4215993

SMILES CCN(CC)Cc1cc(N)ccc1O

InChI Key InChIKey=KRQUHMFZMVSALZ-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50455616   

TargetAcetylcholinesterase(Human)
Tno

Curated by ChEMBL
LigandPNGBDBM50455616(CHEMBL4215993)
Affinity DataKi:  6.30E+3nMAssay Description:Competitive inhibition of recombinant human AChE using varying levels of acetylthiocholine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Tno

Curated by ChEMBL
LigandPNGBDBM50455616(CHEMBL4215993)
Affinity DataKi:  1.60E+4nMAssay Description:Competitive inhibition of AChE in human erythrocytes using varying levels of acetylthiocholine as substrate measured for 1 min by Lineweaver-burk plo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Tno

Curated by ChEMBL
LigandPNGBDBM50455616(CHEMBL4215993)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Tno

Curated by ChEMBL
LigandPNGBDBM50455616(CHEMBL4215993)
Affinity DataKi:  3.74E+4nMAssay Description:Non-competitive inhibition of recombinant human AChE using varying levels of acetylthiocholine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Tno

Curated by ChEMBL
LigandPNGBDBM50455616(CHEMBL4215993)
Affinity DataKi:  3.77E+4nMAssay Description:Non-competitive inhibition of AChE in human erythrocytes using varying levels of acetylthiocholine as substrate measured for 1 min by Lineweaver-burk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Tno

Curated by ChEMBL
LigandPNGBDBM50455616(CHEMBL4215993)
Affinity DataIC50: 4.83E+4nMAssay Description:Inhibition of AChE in human erythrocytes using acetylthiocholine as substrate measured for 1 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProtein kinase C iota type(Human)
Agency For Science, Technology and Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455616(CHEMBL4215993)
Affinity DataIC50: 1.57E+6nMAssay Description:Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed