BDBM50456668 CHEMBL4204959

SMILES COc1cc(ccc1OCCCN1C(=O)c2ccccc2C1=O)-c1nc2ccc(Br)cn2c1NC(C)(C)C

InChI Key InChIKey=JAYGBOWICFYTPB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456668   

TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456668(CHEMBL4204959)
Affinity DataKi:  15nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed