BDBM50456669 CHEMBL4203158

SMILES Cc1cccc2nc(c(NC3CCCCC3)n12)-c1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1

InChI Key InChIKey=JOLPXSKHAOPNGG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50456669   

TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456669(CHEMBL4203158)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456669(CHEMBL4203158)
Affinity DataIC50: 5.93E+3nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed