BDBM50456678 CHEMBL4205452

SMILES Brc1ccc2nc(c(NC3CCCCC3)n2c1)-c1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1

InChI Key InChIKey=PBXJJOYBSKEJPC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50456678   

TargetBeta-secretase 1(Human)
University of Tehran

Curated by ChEMBL
LigandPNGBDBM50456678(CHEMBL4205452)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human BACE1 (1 to 460 residues) expressed in baculovirus expression system using Rh-EVNLDAEFK-quencher as substrate after 90 mins by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed