BDBM50456737 CHEMBL4216860

SMILES COC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1N=C(S[C@@H]1C)c1ccccc1O

InChI Key InChIKey=WSMFZWOSGRIXPV-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50456737   

Target5-hydroxytryptamine receptor 2C(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at 5-HT2C receptor (unknown origin) by calcium release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin) by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) by calcium release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A (unknown origin) receptor after 90 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataKi:  820nMAssay Description:Displacement of [3H]-Mesulergine from human 5-HT2C receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor expressed in HEK cells after 90 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]5-HT from human 5-HT1E receptor expressed in HEK cells after 90 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of The Philippines

Curated by ChEMBL
LigandPNGBDBM50456737(CHEMBL4216860)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]5-CT from human 5-HT1D receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed