BDBM50457178 CHEMBL4209923

SMILES Nc1ccc(cn1)-c1cnc(Cl)c(NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=BGCBAVYVPIXMRK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457178   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Fudan University

Curated by ChEMBL

LigandBDBM50457178(CHEMBL4209923)Copy SMILESCopy InChI

Affinity DataIC50: 52nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by ADP Glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Fudan University

Curated by ChEMBL

LigandBDBM50457178(CHEMBL4209923)Copy SMILESCopy InChI

Affinity DataIC50: 375nMAssay Description:Inhibition of recombinant full length His-tagged human PI3K p110gamma expressed in baculovirus expression system using PIP2/PS as substrate after 1 h...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL