BDBM50457203 CHEMBL4208307

SMILES Nc1nc(nn1C(=O)c1ccccc1)-c1cccnc1

InChI Key InChIKey=OTIFHPVRAWSQPU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50457203   

TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 600nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 210nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 750nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457203(CHEMBL4208307)
Affinity DataIC50: 810nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed