BDBM50457206 CHEMBL4216765

SMILES COc1ccc(cc1)C(=O)n1nc(nc1N)-c1cccnc1

InChI Key InChIKey=AKDDPMDJFJJCDW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50457206   

TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 400nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 50nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.01% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Akron

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human factor 12a using Boc-Gly-Gln-Arg-AMC substrate incubated for 1 hr in presence of 0.02% Tween20 surfactant by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50457206(CHEMBL4216765)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of EGFR (unknown origin) infected in insect sf9 cells incubated for 1 hrs in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed