BDBM50457450 CHEMBL4204780

SMILES C[C@H](NC(=O)c1ncnc(N)c1Cl)c1ncc(s1)C(=O)Nc1cc(c(Cl)cn1)C(F)(F)F

InChI Key InChIKey=VWMJHAFYPMOMGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50457450   

TargetSerine/threonine-protein kinase B-raf(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM50457450(CHEMBL4204780)
Affinity DataIC50: 70nMAssay Description:Inhibition of BRAF V600E mutant in human PLGA cells assessed as reduction in ERK phosphorylation after 1 hr by mass spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed