BDBM50457719 CHEMBL4215377

SMILES CN1CCC(CC1)Nc1cc(nc2cc(OCCCN3CCCC3)c(Cl)cc12)-c1ccc(C)o1

InChI Key InChIKey=FKRRYTPCUFOKGU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50457719   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457719(CHEMBL4215377)
Affinity DataIC50: 298nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457719(CHEMBL4215377)
Affinity DataIC50: 342nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457719(CHEMBL4215377)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Tracer Red binding to human ERG in membranes after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed