BDBM50457728 CHEMBL4205107

SMILES COc1cc2c(NCCO)cc(nc2cc1OCCCN1CCCC1)-c1ccc(C)o1

InChI Key InChIKey=PCKQRGGTJLXKRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457728   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457728(CHEMBL4205107)
Affinity DataIC50: 244nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457728(CHEMBL4205107)
Affinity DataIC50: 781nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed