BDBM50457732 CHEMBL4205136

SMILES CCc1ccc(o1)-c1cc(NC2CCN(C)CC2)c2cc(OC)c(OCCCN3CCC4(CC4)C3)cc2n1

InChI Key InChIKey=BBJDFTWFOONSLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457732   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457732(CHEMBL4205136)
Affinity DataIC50: 599nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Wuxi Apptec (Tianjin) Co.

Curated by ChEMBL
LigandPNGBDBM50457732(CHEMBL4205136)
Affinity DataIC50: 212nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed