BDBM50457776 CHEMBL4208646

SMILES COc1ccc(cc1-c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1)C1CC(=O)c2c(O)cc(O)cc2O1

InChI Key InChIKey=OUTWZGVRBJVENE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50457776   

Target72 kDa type IV collagenase(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457776(CHEMBL4208646)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457776(CHEMBL4208646)
Affinity DataIC50: 7.43E+4nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Guangxi Normal University

Curated by ChEMBL
LigandPNGBDBM50457776(CHEMBL4208646)
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed