BDBM50457887 CHEMBL4214728

SMILES Nc1nc(N2CCN(CC2)C(=O)Nc2ccc(OC(F)(F)F)cc2)c2ncsc2n1

InChI Key InChIKey=UVTJYKFIWBZRDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457887   

TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457887(CHEMBL4214728)
Affinity DataIC50: 331nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50457887(CHEMBL4214728)
Affinity DataIC50: 548nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed