BDBM50457930 CHEMBL4208864

SMILES Fc1cccc(F)c1-c1nc2cc(ccc2c(=O)o1)C(F)(F)F

InChI Key InChIKey=XAWFWAWHYUKPSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50457930   

TargetCoagulation factor VII/Tissue factor(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50457930(CHEMBL4208864)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of tissue factor/factor 7a (unknown origin)-induced factor 10 activation using S-2765 as substrate preincubated for 5 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50457930(CHEMBL4208864)
Affinity DataIC50: 1.34E+5nMAssay Description:Inhibition of thrombin (unknown origin) using S-2238 as substrate measured for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50457930(CHEMBL4208864)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibition of factor 10a (unknown origin) using S-2765 as substrate measured for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed