BDBM50457980 CHEMBL4202725

SMILES O=C(Nc1ccccc1-n1cc(nn1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=PWPQYHFUVPQSBU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457980   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Rheinische Friedrich-Wilhelms-Universit£T Bonn

Curated by ChEMBL
LigandPNGBDBM50457980(CHEMBL4202725)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of C-terminal GFP-fused human ABCG2 expressed in MDCK2 cells preincubated for 30 mins followed by Hoechst 33342 addition and measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Rheinische Friedrich-Wilhelms-Universit£T Bonn

Curated by ChEMBL
LigandPNGBDBM50457980(CHEMBL4202725)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of ABCB1 in human A2780adr cells assessed as reduction in calcein AM levels preincubated for 30 mins followed by calcein AM addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed