BDBM50458456 CHEMBL4217617

SMILES COc1ccc(Cn2cc(C(=O)NCCCCCCCNc3c4CCCCc4nc4ccc(OC)cc34)c(=O)c3ccccc23)cc1

InChI Key InChIKey=SGRUENDUBYUMQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458456   

TargetAcetylcholinesterase(Human)
University of Defence

Curated by ChEMBL
LigandPNGBDBM50458456(CHEMBL4217617)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Defence

Curated by ChEMBL
LigandPNGBDBM50458456(CHEMBL4217617)
Affinity DataIC50: 1.14E+4nMAssay Description:Antagonist activity at human M1 mAChR expressed in CHO cells assessed as inhibition of oxotremorine M-stimulated calcium influx preincubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Defence

Curated by ChEMBL
LigandPNGBDBM50458456(CHEMBL4217617)
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibition of human plasmatic BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed