BDBM50458950 CHEMBL77510::Pyridine-2-Carbaldehyde Oxime

SMILES O\N=C\c1ccccn1

InChI Key InChIKey=MTFJSAGADRTKCI-UHFFFAOYSA-N

Data  1 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50458950   

TargetAcetylcholinesterase(Human)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50458950(CHEMBL77510 | Pyridine-2-Carbaldehyde Oxime)
Affinity DataKd:  2.10E+5nMAssay Description:Reactivation of NIMP-inhibited human recombinant AChE assessed as dissociation constant of inhibited enzyme-compound complex incubated for 1 to 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50458950(CHEMBL77510 | Pyridine-2-Carbaldehyde Oxime)
Affinity DataKd:  2.10E+5nMAssay Description:Reactivation of VX-inhibited human recombinant AChE assessed as dissociation constant of inhibited enzyme-compound complex incubated for 1 to 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50458950(CHEMBL77510 | Pyridine-2-Carbaldehyde Oxime)
Affinity DataKd:  4.00E+5nMAssay Description:Reactivation of ethyl paraoxon-inhibited human recombinant AChE assessed as dissociation constant of inhibited enzyme-compound complex incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50458950(CHEMBL77510 | Pyridine-2-Carbaldehyde Oxime)
Affinity DataIC50: 5.60E+5nMAssay Description:Inhibition of human recombinant AChE by spectrophotometry based Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50458950(CHEMBL77510 | Pyridine-2-Carbaldehyde Oxime)
Affinity DataKd:  7.90E+5nMAssay Description:Reactivation of tabun-inhibited human recombinant AChE assessed as dissociation constant of inhibited enzyme-compound complex incubated for 1 to 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed