BDBM50458955 CHEMBL4209192

SMILES CCC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC3CCCC3)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O

InChI Key InChIKey=QIWKCZYPLMKZJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458955   

TargetSerine/threonine-protein kinase PLK1(Human)
University of Massachusetts-Boston

Curated by ChEMBL
LigandPNGBDBM50458955(CHEMBL4209192)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant PLK1 by Z-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Massachusetts-Boston

Curated by ChEMBL
LigandPNGBDBM50458955(CHEMBL4209192)
Affinity DataIC50: 596nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) incubated for 1 hr by AlphaScreen biotin-JQ1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
University of Massachusetts-Boston

Curated by ChEMBL
LigandPNGBDBM50458955(CHEMBL4209192)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of BRDT-BD1 (unknown origin) incubated for 1 hr by AlphaScreen biotin-JQ1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed