BDBM50458960 CHEMBL4216875

SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)[C@H](C)N(C3CCCC3)c2n1)C(=O)NC1CCN(C)CC1

InChI Key InChIKey=DYQPKOGFUIEBMS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50458960   

TargetSerine/threonine-protein kinase PLK1(Human)
University of Massachusetts-Boston

Curated by ChEMBL
LigandPNGBDBM50458960(CHEMBL4216875)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human recombinant PLK1 by Z-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Massachusetts-Boston

Curated by ChEMBL
LigandPNGBDBM50458960(CHEMBL4216875)
Affinity DataIC50: 107nMAssay Description:Inhibition of BRD4-BD1 (unknown origin) incubated for 1 hr by AlphaScreen biotin-JQ1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
University of Massachusetts-Boston

Curated by ChEMBL
LigandPNGBDBM50458960(CHEMBL4216875)
Affinity DataIC50: 229nMAssay Description:Inhibition of BRDT-BD1 (unknown origin) incubated for 1 hr by AlphaScreen biotin-JQ1 competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed