BDBM50459192 CHEMBL4205724

SMILES COc1cncc(NC(C(=O)c2c[nH]c3ccccc23)c2ccccc2)c1

InChI Key InChIKey=FHGKXWSNTAZCCJ-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50459192   

TargetCytochrome P450 3A4(Human)
Cistim Leuven

Curated by ChEMBL

LigandBDBM50459192(CHEMBL4205724)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
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TargetCytochrome P450 2C19(Human)
Cistim Leuven

Curated by ChEMBL

LigandBDBM50459192(CHEMBL4205724)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
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TargetCytochrome P450 1A2(Human)
Cistim Leuven

Curated by ChEMBL

LigandBDBM50459192(CHEMBL4205724)Copy SMILESCopy InChI

Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy BDB DOIPubMed
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TargetCytochrome P450 2C9(Human)
Cistim Leuven

Curated by ChEMBL

LigandBDBM50459192(CHEMBL4205724)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Cistim Leuven

Curated by ChEMBL

LigandBDBM50459192(CHEMBL4205724)Copy SMILESCopy InChI

Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
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TargetCytochrome P450 2D6(Human)
Cistim Leuven

Curated by ChEMBL

LigandBDBM50459192(CHEMBL4205724)Copy SMILESCopy InChI

Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL