BDBM50459236 CHEMBL4203007

SMILES [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCCC(C)(C)O

InChI Key InChIKey=RCOOUPCIIFDFER-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50459236   

TargetAlpha-crystallin B chain(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  57nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAlpha-crystallin A chain(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  36nMAssay Description:Induction of redissolving of aggregated alpha-crystallin A Y118D mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAlpha-crystallin B chain(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  3.12E+3nMAssay Description:Induction of redissolving of aggregated alpha-crystallin B R120G mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed